Research Library

This study compared the effects of probiotics versus autologous fecal microbiome transplantation (aFMT) on gut microbiome recovery after antibiotic use in mice and humans. Probiotics delayed gut microbiome and gene expression recovery, while aFMT resulted in a rapid and near-complete recovery. These findings suggest that probiotics may hinder post-antibiotic gut recovery, highlighting the need for alternative approaches like aFMT or personalized probiotics.

The Companion Animal FMT Consortium aims to increase accessibility of FMT as a microbial-directed therapeutic for dogs and cats by simplifying and demystifying the process of performing FMT in clinical practice. These FMT clinical guidelines are intended for veterinarians in a variety of clinical practice types and can be modified and adapted as needed to align with financial and technical resources available to individual practitioners.